TORONTO & SAN JOSE, Calif.--(BUSINESS WIRE)--May 9, 2002--MDS
Proteomics, a proteomics-based drug discovery company, and Thermo
Finnigan, a Thermo Electron business (NYSE:TMO - news) and leading
manufacturer of mass spectrometry instruments, today announced that
they will collaborate on the design of new technology that will
greatly accelerate the analysis of low-abundant proteins -- proteins
that are most often associated with human disease. MDS Proteomics'
experts in proteomics-based analyses will work with Thermo Finnigan's
world-class engineering team to customize Thermo Finnigan FTMS
instruments for MDS Proteomics' unique applications. This new
technology, which is based on Fourier transform ion cyclotron
resonance mass spectrometry (FTMS), significantly enhances analytical
sensitivity, providing a several-thousand-fold boost in mass
spectrometric resolution, a 50-fold improvement in mass measurement
accuracy, and 100-fold improvement in the dynamic range detection of
these trace proteins. MDS Proteomics will deploy the customized FTMS
systems to dramatically reduce the time and effort required for
drug-target discovery and therapeutic validation.
MDS Proteomics will contribute technical specifications pertaining
to FTMS technology requirements for proteomic applications and receive
exclusive access to beta versions of Thermo Finnigan's FTMS
instruments. MDS Proteomics' evaluation and feedback during the early
assessment period will provide Thermo Finnigan with important input as
it develops a commercial FTMS product. The Thermo Finnigan FTMS
proteomics platform will provide high dynamic range, accurate mass
measurement, high mass resolution, and ultra-high sensitivity together
with peptide sequencing capability, allowing unsurpassed low-level
protein identification and a reduction in the overall analysis time.
The combination of these breakthrough performance attributes will
enable MDS Proteomics to more rapidly identify disease-specific
proteins that are often present at trace quantities in human tissues.
"We are very excited by the opportunity to add Thermo Finnigan's
proprietary technology to our already unique network of mass
spectrometry systems supplied by Applied Biosystems/MDS Sciex
Instruments," said Frank Gleeson, CEO and president of MDS
Proteomics. "Together with these key partners, MDSP has developed mass
spectrometry systems that are 10,000-times more sensitive and
100-times faster at identifying proteins and their interacting
partners, representing a two-year lead time advantage over competing
systems. This means we can now apply proteomics directly to
accelerating the drug-discovery process in multiple ways. We plan to
leverage the capabilities and expertise of both mass spectrometry
technology platforms with our in-house biological and supercomputing
capabilities to improve the productivity of the pharmaceutical
industry in discovering and developing new medicines for the treatment
of disease."
"We have a strong interest in working with MDS Proteomics, who are
visionary leaders in developing novel applications for proteomics in
drug discovery," said Ian Jardine, president of Thermo Finnigan. "Our
ion trap mass spectrometers, many of which are currently used by MDS
Proteomics for high-throughput analysis, are recognized as workhorse
instruments in the field of proteomics. FTMS technology will give us
another strong platform to serve researchers in protein science and
proteomics. MDS Proteomics will provide us with valuable insights into
market needs and applications as we develop FTMS."
About Thermo Finnigan
Thermo Finnigan is a leading supplier of total laboratory
solutions for the analytical and life sciences industries. Product
offerings include mass spectrometers, liquid chromatography equipment,
gas chromatography equipment and multi-instrument combinations of
these products, as well as a complete range of advanced software
solutions. More information is available at
www.thermo.com/thermofinnigan.
About Thermo Electron
Thermo Electron Corporation is a global leader in providing
technology-based instruments, components, and systems that offer total
solutions for markets ranging from life sciences to telecommunications
to food, drug, and beverage production. The company's powerful
technologies help researchers sift through data to make discoveries
that will fight disease or prolong life. They allow manufacturers to
fabricate critical components required to increase the speed and
quality of communications. And they automatically monitor and control
online production to ensure that quality standards are met safely and
efficiently. Thermo Electron, based in Waltham, Mass., reported $2.2
billion in revenues in 2001 and employs approximately 12,000 people
worldwide. For more information on Thermo Electron, visit
www.Thermo.com.
About MDS Proteomics
A pioneer in the field of proteomic-enabled drug discovery, MDS
Proteomics' goal is to transform the productivity of the
pharmaceutical industry in discovering and developing new medicines
for the treatment of disease. The company has developed exceptional
capabilities in proteomics systems, technology, supercomputing, drug
design, screening and biology and is uniquely positioned to build an
effective bridge between gene discovery and therapeutic development.
This distinctive capability is being used in collaborations with
pharmaceutical and biotechnology companies as well as for the
development of the company's own product pipeline. In its proteomics
facilities in Europe and North America, the company focuses on drug
target discovery and validation for both antibody and small molecule
therapeutics. MDS Proteomics is a majority-owned subsidiary of MDS
Inc. For more information on MDS Proteomics, visit the company's
Website at www.mdsp.com.
About MDS Inc.
MDS Inc. (NYSE:MDZ - news; TSE:MDS - news) is an international health and life
sciences company. Its products and services include: laboratory
testing, imaging agents for nuclear medicine testing, sterilization
systems for medical and consumer products, research and clinical
development services for planning and delivery of cancer treatment,
analytical instruments to assist in the development of new drugs, and
medical/surgical supplies. MDS employs more than 10,000 highly skilled
people at its global operations on four continents. Detailed
information about the company is available at the MDS Website at
www.mdsintl.com.
The following constitutes a "Safe Harbor" statement under the
Private Securities Litigation Reform Act of 1995: This press release
contains forward-looking statements that involve a number of risks and
uncertainties. Important factors that could cause actual results to
differ materially from those indicated by such forward-looking
statements are set forth under the heading "Forward-Looking
Statements" in Thermo Electron's Annual Report on Form 10-K for the
fiscal year ended December 29, 2001. These include risks and
uncertainties relating to: integration of the company's instrument
businesses, implementation of the company's strategies for improving
internal growth, the company's guarantee of obligations of a
subsidiary that was spun off, the effect of exchange rate fluctuations
on international operations, potential impairment of goodwill, the
need to develop new products and adapt to significant technological
change, dependence on customers that operate in cyclical industries,
the effect of changes in governmental regulations, and dependence on
customers' capital spending policies and government funding policies.
We undertake no obligation to publicly update any forward-looking
statement, whether as a result of new information, future events, or
otherwise.
Contact:
MDS Proteomics
Debora Smith, 416/646-6349
dsmith@mdsp.com
or
Thermo Finnigan
Wendy Weise, 408/965-6577
wweise@thermofinnigan.com